from obnb.data.network.base import BaseNDExData
from obnb.typing import Converter
[docs]class SIGNOR(BaseNDExData):
"""The SIGnaling Network Open Resource human gene interaction network."""
cx_uuid = "523fff27-afe8-11e9-8bb4-0ac135e8bacf"
def __init__(
self,
root: str,
*,
weighted: bool = False,
directed: bool = False,
largest_comp: bool = True,
gene_id_converter: Converter = "HumanEntrez",
**kwargs,
):
"""Initialize the SIGNOR network data."""
super().__init__(
root,
weighted=weighted,
directed=directed,
largest_comp=largest_comp,
gene_id_converter=gene_id_converter,
cx_kwargs={
"interaction_types": [
"down-regulates activity",
"down-regulates quantity by destabilization",
"down-regulates quantity by repression",
"down-regulates quantity",
"down-regulates",
"form complex",
"unknown",
"up-regulates activity",
"up-regulates quantity by expression",
"up-regulates quantity by stabilization",
"up-regulates quantity",
"up-regulates",
],
"node_id_prefix": "uniprot",
"node_id_entry": "r",
},
**kwargs,
)