from obnb.alltypes import Converter
from obnb.data.network.base import BaseNDExData
[docs]class HIPPIE(BaseNDExData):
"""The HIPPIE Human scored Protein Protein Interaction network.
Note: the inferred PPI directionality is disregarded, i.e. the resulting
network is undirected.
"""
cx_uuid = "89dd3925-3718-11e9-9f06-0ac135e8bacf"
def __init__(
self,
root: str,
*,
weighted: bool = True,
directed: bool = False,
largest_comp: bool = True,
gene_id_converter: Converter = "HumanEntrez",
**kwargs,
):
"""Initialize the HIPPIE network data."""
super().__init__(
root,
weighted=weighted,
directed=directed,
largest_comp=largest_comp,
gene_id_converter=gene_id_converter,
cx_kwargs={
"interaction_types": ["interacts-with"],
"node_id_prefix": "entrez gene",
"default_edge_weight": 0.0,
"edge_weight_attr_name": "Confidence Value",
"reduction": "max",
},
**kwargs,
)